某地区犬巴贝斯虫病的调查某地区犬巴贝斯虫病的调查及临床常用药物的疗效观察(附件)【字数：6229】
1犬巴贝斯虫（Babesia spp.）病，又称犬血焦虫病，犬蜱虫病，血孢子虫病，是一种经蜱虫传播，由梨形虫纲巴贝斯科原虫寄生在犬血液内所引起的具有季节性和流行性的寄生虫病。其主要临床症状表现为高热、贫血、血红蛋白尿、消瘦等，严重者可引起犬只死亡。本病分布广泛，在我国江苏、河南的部分地区呈地方流行。在南京地区该病多发于有蜱区域，特别是在蜱的活跃期春秋季节，疫情较为严重。目前，本病尚无有效疫苗，主要杀虫药为贝尼尔，但易产生耐药性。本文通过调查南京某宠物医院本病的临床病例，发现南京地区犬巴贝斯虫病的多发期是4~11月份，其中9、10月份发病患犬数明显高于其他月份；在临床上常用的几种犬巴贝斯虫杀虫药中，传统特效药贝尼尔的药效大不如前，红典提高红细胞和血红蛋白数量的效果较显著，其他几种药物的效果没有较大差异，这些结论为本病的预防及临床治疗提供了依据。
目 录
Abstract1
Key words1
引言（或绪论）2
1□材料与方法2
1.1□材料 2
1.1.1□病例来源2
1.1.2□主要药物和器材2
1.2□方法 2
1.2.1□临床病例调查2
1.2.2□临床检查2
1.2.3□实验室检查3
1.2.4□治疗效果观察3
2□结果与分析3
2.1□发病时间分布3
2.2□临床常用药物的疗效观察结果6
3□讨论 7
3.1□流行病学调查7
3.2□犬巴贝斯虫病杀虫药7
3.3□犬巴贝斯虫病的预防8
致谢8
参考文献8
南京地区犬巴贝斯虫病的调查及临床常用药物的疗效观察
动物药学专业学生 朱 梅
指导教师 孙卫东
Investigation of Canine Babesiosis and Observation of Curative Effect of Clinical Common Drugs in Nanjing
Student majoring in anima *好棒文|www.hbsrm.com +Q: #351916072#
l pharmacy ZHU Mei
Tutor SUN Weidong
Abstract：Canine babesiosis, also known as canine blood piroplasmosis, canine tick disease, blood sporozoan disease, is a kind of transmission through tick, the pearshaped worm steel barber, protozoa parasitism in dog blood with seasonal and pandemic caused by parasitic diseases. As the main clinical symptoms: high fever, anemia, hemoglobinuria and angular, etc. Severe cases can lead to animal death. The disease is widely distributed,endemic in parts of Jiangsu and Henan. The disease happens in all regions of Nanjing have ticks. especially in active period in spring and autumn, the epidemic is much more serious. At present, there is no effective vaccine of the disease. The main pesticide is Berenil, but easy to produce drug resistance. Through investigating the clinical case of a pet hospital in nanjing, this article found that the multiple period of canine babesiosis was from April to November and The number of patients with the disease was significantly higher in September and October than in other months;among the clinical commonly used drugs for Canine babesiosis, the effect of the traditional special medicine, Berenil, is not as good as before, the effect of HongDian increasing the number of red blood cells and hemoglobin is significant,and theres no big difference in the effect of several other drugs .These results provide the basis for prevention and clinical treatment of this disease.
Key words: canine; babesiosis; Berenil; investigation of clinical cases; comparative effectiveness
犬巴贝斯虫（Babesia spp.）病，又称犬血焦虫病，犬蜱虫病，血孢子虫病，是一种经蜱虫传播，由梨形虫纲巴贝斯科原虫寄生在犬血液内所引起的具有季节性和流行性的寄生虫病[1, 2]。病原有犬巴贝斯虫、吉氏巴贝斯虫和韦氏巴贝斯虫三种。（1）犬巴贝斯虫：虫体较大，一般长4~5 μm，最长可达7 μm。典型虫体为梨籽形，两虫尖端以锐角相连，每个红细胞内的虫体数目为1~16个。（2）吉氏巴贝斯虫：虫体很小，多呈环形，呈梨籽形的很少，一个红细胞内最多可寄生30个虫体。（3）韦氏巴贝斯虫：除虫体略大外，形态与犬巴贝斯虫相似。其主要临床症状表现为：高热、贫血、血红蛋白尿、消瘦等。严重者可引起动物死亡。
目 录
Abstract1
Key words1
引言（或绪论）2
1□材料与方法2
1.1□材料 2
1.1.1□病例来源2
1.1.2□主要药物和器材2
1.2□方法 2
1.2.1□临床病例调查2
1.2.2□临床检查2
1.2.3□实验室检查3
1.2.4□治疗效果观察3
2□结果与分析3
2.1□发病时间分布3
2.2□临床常用药物的疗效观察结果6
3□讨论 7
3.1□流行病学调查7
3.2□犬巴贝斯虫病杀虫药7
3.3□犬巴贝斯虫病的预防8
致谢8
参考文献8
南京地区犬巴贝斯虫病的调查及临床常用药物的疗效观察
动物药学专业学生 朱 梅
指导教师 孙卫东
Investigation of Canine Babesiosis and Observation of Curative Effect of Clinical Common Drugs in Nanjing
Student majoring in anima *好棒文|www.hbsrm.com +Q: #351916072#
l pharmacy ZHU Mei
Tutor SUN Weidong
Abstract：Canine babesiosis, also known as canine blood piroplasmosis, canine tick disease, blood sporozoan disease, is a kind of transmission through tick, the pearshaped worm steel barber, protozoa parasitism in dog blood with seasonal and pandemic caused by parasitic diseases. As the main clinical symptoms: high fever, anemia, hemoglobinuria and angular, etc. Severe cases can lead to animal death. The disease is widely distributed,endemic in parts of Jiangsu and Henan. The disease happens in all regions of Nanjing have ticks. especially in active period in spring and autumn, the epidemic is much more serious. At present, there is no effective vaccine of the disease. The main pesticide is Berenil, but easy to produce drug resistance. Through investigating the clinical case of a pet hospital in nanjing, this article found that the multiple period of canine babesiosis was from April to November and The number of patients with the disease was significantly higher in September and October than in other months;among the clinical commonly used drugs for Canine babesiosis, the effect of the traditional special medicine, Berenil, is not as good as before, the effect of HongDian increasing the number of red blood cells and hemoglobin is significant,and theres no big difference in the effect of several other drugs .These results provide the basis for prevention and clinical treatment of this disease.
Key words: canine; babesiosis; Berenil; investigation of clinical cases; comparative effectiveness
犬巴贝斯虫（Babesia spp.）病，又称犬血焦虫病，犬蜱虫病，血孢子虫病，是一种经蜱虫传播，由梨形虫纲巴贝斯科原虫寄生在犬血液内所引起的具有季节性和流行性的寄生虫病[1, 2]。病原有犬巴贝斯虫、吉氏巴贝斯虫和韦氏巴贝斯虫三种。（1）犬巴贝斯虫：虫体较大，一般长4~5 μm，最长可达7 μm。典型虫体为梨籽形，两虫尖端以锐角相连，每个红细胞内的虫体数目为1~16个。（2）吉氏巴贝斯虫：虫体很小，多呈环形，呈梨籽形的很少，一个红细胞内最多可寄生30个虫体。（3）韦氏巴贝斯虫：除虫体略大外，形态与犬巴贝斯虫相似。其主要临床症状表现为：高热、贫血、血红蛋白尿、消瘦等。严重者可引起动物死亡。
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